Bladder Cancer Xenograft Models Available
Several PDX models are available for bladder cancer, including xenografts that are muscle-invasive. These models all follow the overall structure and morphology of the source human tumors when engrafted at a low passage number into immunocompromised mice.
Request formal project quotation from Altogen Labs CRO.
|Urothelial Carcinoma TP53||TP53, ATM, FLT3, PTPN11|
|Urothelial Carcinoma invasive|
TP53—tumor suppressor p53: Mutations in p53 lead to genomic instability and lower sensitivity to DNA damaging agents.
ATM—ataxia-telangiectasia mutated: Plays a central role in response to chemical and ionizing-radiation induced DNA damage. Mutations in ATM increase sensitivity to ionizing radiation.
Click here to request bladder cancer xenograft project quote from Altogen Labs CRO.